If you’re bitten by an assassin bug, it’s important to act quickly. Start by gently washing the bite area with soap and water to reduce the risk of infection. Applying a cold compress—like a wrapped ice pack—can help numb the pain and reduce swelling. Be sure not to place ice directly on the skin. Over-the-counter antihistamines may relieve itching and swelling, and if the pain continues, pain relievers such as ibuprofen or acetaminophen can help.

After treating the bite, keep an eye on the area for signs of complications. If you notice increasing redness, warmth, pus, or swelling, it may be infected and need medical attention. In rare cases, some people may experience allergic reactions, including difficulty breathing, dizziness, or widespread swelling—these symptoms require immediate medical care. Assassin bugs can also transmit Chagas disease, particularly in Central and South America. If you develop a fever, fatigue, or swelling around the eyes after a bite, consult a healthcare provider right away.

To prevent future bites, use insect repellent when spending time outdoors in areas known for assassin bugs. Wear long sleeves and pants, especially in wooded or grassy environments. At home, check for cracks or gaps in windows, doors, and walls, and inspect sleeping areas for any signs of bugs to ensure a safe space.

Taking these steps can help minimize discomfort and protect you from potential complications linked to assassin bug bites.